Research Research Programs Biotechnology, Imaging & Drug Development Systems, Pathways & Targets Cancer Control Clinical Research Stern Center for Cancer Clinical Trials and Research Disease-Oriented Teams Protocol Review and Monitoring Committee Research Resources Membership Guidelines Shared Resources Acknowledgement of Grant and Shared Resources Anti-Cancer Challenge Research Anti-Cancer Challenge Pilot Research Projects Anti-Cancer Challenge Past Awardees Team Funds Centers & Institutes Space Management and Requests Funding Opportunities Anti-Cancer Challenge Pilot Projects Home Research Anti-Cancer Challenge Pilot Research Projects Applications Due March 6, 2023 The overall objectives of the CFCCC ACC Pilot Project Program are to: (1) increase the number of extramural peer-reviewed grant awards, particularly collaborative and multi-PI grants; (2) support the development of investigator-initiated early phase clinical trial protocols by clinical investigators, particularly interventional trials; (3) advance novel diagnostic or screening technologies, therapeutic molecules or devices, and bio-behavioral interventions from bench to bedside; and (4) advance research on cancer control, cancer population science, and pediatric cancers. Download the RFP Submit Your Letter of Intent (optional) Download the Proposal Template (required) APPLY NOW SPECIAL INTEREST AREA: COMMUNITY ENGAGEMENT Of special interest are projects where engagement of communities informs and results in high-impact science. This includes projects with community partners and/or projects that engage community stakeholders in research development, methods, analyses, dissemination of results, and/or implementation of evidence-based interventions. CFCCC hosted a webinar for applicants to learn more about engaging communities in research on January 30, 2023. Review the webinar recording and slide deck. Basic Eligibility Requirements AWARD TYPES Applicants may apply to one of these five distinct opportunities. Investigators may only submit one application as a PI. AWARD ELIGIBILITY CRITERIA REVIEW CRITERIA Early-Stage Investigator Award $20,000 Download the RFPSubmit LOI (optional)APPLY NOW This opportunity provides support for early-stage investigators. The PI must meet the basic eligibility requirements and be an early-stage investigator (ESI) as defined by NIH: Must have completed their terminal research degree or end of post-graduate clinical training, whichever is later, within the last 10 years Must not have previously competed successfully as PI for a substantial NIH independent research award Standard Award review criteria apply. ESI applications will be reviewed in a separate pool. In addition, peer reviewers are instructed to focus more on the proposed approach than on track record, and to expect less preliminary data than would be provided by established investigators. Standard Award $40,000 Download the RFPSubmit LOI (optional)APPLY NOW This opportunity provides support for investigators at all levels. The PI must meet the basic eligibility requirements. Applications will be peer reviewed in accordance with NIH’s scoring system with explicit emphasis placed on the near-term impact (i.e., within 1-2 years). Applicants will receive a copy of the review comments in an anonymous format. Projects that address one or more of the priority areas will be scored more favorably. Projects that extend basic science to a clinical or translational capacity, leverage CFCCC Shared Resources, collaborate with DOTs, or involve significant new collaborations will be ranked more favorably. Inter/intra-programmatic collaboration between Cancer Center members are strongly encouraged. Underrepresented Investigator Award $40,000 Download the RFPSubmit LOI (optional)APPLY NOW This opportunity provides support for: Investigators from historically disenfranchised racial and ethnic groups that are under-represented in health sciences and cancer research, Individuals with physical or mental disabilities that substantially limits one or more major life activities, or Those with a personal or professional background of economic disadvantage Refer to the NIH operational definitions of under-represented groups. Research can be in any area relevant to the RFP. Standard Award review criteria apply. Re-entry After Family Care Award $40,000 Download the RFPSubmit LOI (optional)APPLY NOW This opportunity provides support for investigators whose research has been interrupted for at least 6 months by significant but temporary family care responsibilities (e.g., childbirth; childbearing complications; child-rearing; caring for an ill, disabled, or elderly family member). Funds are meant to provide support for ongoing research and assist with addressing gaps in research productivity (e.g., obtaining preliminary data for grant submission). Applicants must demonstrate a compelling need that is related to research activity interruption due to caregiving responsibilities and are expected to describe the caregiving burden and impact of this caregiving on capacity to conduct research and/or financially support their research program. Standard Award review criteria apply. Multi-PI (Team Science) Award $60,000 Download the RFPSubmit LOI (optional)APPLY NOW This important opportunity provides support for activities that require a team science approach. The goal is to encourage collaboration among equals and preparation of competitive applications for larger extramural awards. The PIs must meet the basic eligibility requirements, demonstrate shared responsibility and authority for leading the project, and identify the extramural award application the proposed research will support. Applicants are encouraged to contact CFCCC prior to submission to discuss the appropriateness of their proposed research for this opportunity. Standard Award review criteria apply. In addition, peer reviewers are instructed to evaluate whether the scientific goals of the project justify a multi-PI (team science) approach. As with NIH P01 applications, it is expected that the multiple components of the applications are stronger together than if submitted separately. About the UCI Anti-Cancer Challenge Every penny of the funds raised by Anti-Cancer Challenge participants are directed towards advancing innovative basic, translational and clinical cancer research that will lead to the next breakthroughs in cancer treatment. Learn more about the ACC Challenge, past awardees, and team funds here.