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Protocol Review and Monitoring Committee

The CFCCC’s Protocol Review and Monitoring Committee (PRMC) is responsible for the scientific and feasibility review of cancer-related protocols and has the sole authority to authorize activation of clinical studies. All cancer-related clinical research studies must receive PRMC approval prior to activation. The PRMC consists of qualified UCI faculty and staff with the necessary level of expertise within each respective scientific research area.

The Stern Center’s Protocol Review and Monitoring Unit provides administrative management and support to the CFCCC’s comprehensive system of research oversight, including the PRMC.

Please contact us with questions or for assistance with submitting your protocol at

2024 PRMC Schedule

Full-Committee meetings occur once per month with additional quarterly meetings. The deadline for submission of protocols that require review by the full committee is 2 weeks prior to the meeting date.

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PRMC Application

Investigators must submit all cancer-related hypothesis-driven clinical research studies to the CFCCC for initial review by the PRMC prior to activation. PRMC also reviews open protocols on an annual basis on a schedule that aligns with IRB renewal.

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2024 DSMB Schedule

Full-committee meetings occur bi-monthly.

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