Notice of Special Interest (NOSI): RNA Modifications in Cancer Biology The purpose of this Notice of Special Interest (NOSI) is to stimulate research on the role of RNA modifications in the area of cancer biology. Despite the recognition that RNA modifications and editing exert substantial impact on gene expression and function, there are a lack of mechanistic insights into the dynamic regulation of RNA modifications and how their de-regulation drives cancer formation. A better understanding of the extent, diversity and crosstalk between different types of RNA modification, and the elucidation of the molecular players that read and interpret the modification code are needed to reveal the mechanisms of RNA modifications that underly cancer formation and the cancer phenotype. Application and Submission Information: Submit applications for this initiative using one of the following funding opportunity announcements (FOAs) through the expiration date of this notice. Activity Code FOA Title First Available Due Date R21 PA-20-195 NIH Exploratory/Development Research Grant Program (Parent R21 Clinical Trial Not Allowed) February 16, 2022 R03 PAR-20-052 NCI Small Grants Program for Cancer Research for Years 2020, 2021, and 2022 (NCI Omnibus R03 Clinical Trial Optional) February 24, 2022 R61 RFA-CA-22-001 Innovative Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed) April 22, 2022 R33 RFA-CA-22-002 Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed) April 22, 2022 More Info Expiration Date: May 08, 2023 - 5:00:PM NOT-CA-22-003 Agency National Institutes of Health (NIH) Type Federal Disciplines Basic Science
Notice of Special Interest (NOSI): RNA Modifications in Cancer Biology The purpose of this Notice of Special Interest (NOSI) is to stimulate research on the role of RNA modifications in the area of cancer biology. Despite the recognition that RNA modifications and editing exert substantial impact on gene expression and function, there are a lack of mechanistic insights into the dynamic regulation of RNA modifications and how their de-regulation drives cancer formation. A better understanding of the extent, diversity and crosstalk between different types of RNA modification, and the elucidation of the molecular players that read and interpret the modification code are needed to reveal the mechanisms of RNA modifications that underly cancer formation and the cancer phenotype. Application and Submission Information: Submit applications for this initiative using one of the following funding opportunity announcements (FOAs) through the expiration date of this notice. Activity Code FOA Title First Available Due Date R21 PA-20-195 NIH Exploratory/Development Research Grant Program (Parent R21 Clinical Trial Not Allowed) February 16, 2022 R03 PAR-20-052 NCI Small Grants Program for Cancer Research for Years 2020, 2021, and 2022 (NCI Omnibus R03 Clinical Trial Optional) February 24, 2022 R61 RFA-CA-22-001 Innovative Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed) April 22, 2022 R33 RFA-CA-22-002 Advanced Development and Validation of Emerging Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed) April 22, 2022 More Info Expiration Date: May 08, 2023 - 5:00:PM NOT-CA-22-003 Agency National Institutes of Health (NIH) Type Federal Disciplines Basic Science